Stimulation of the Peripheral Nervous SystemStimulation of the Peripheral Nervous System



This book will be of great value to all those who deal with neuromodulation, including clinicians who select PNS candidates, surgeons and other specialists who implant PNS devices, and researchers and engineers who work on making the ...

Author: K.V. Slavin

Publisher: Karger Medical and Scientific Publishers

ISBN: 9783318028096

Category:

Page: 244

View: 535

Among neuromodulation procedures, electrical stimulation of peripheral nerves (PNS) is probably the most underappreciated modality. Although PNS is used for all kinds of medical conditions, ranging from chronic neuropathic pain and headache to epilepsy, depression, hypertension and heart failure, its importance is frequently overshadowed by spinal cord stimulation and deep brain stimulation. While the earlier version of this book dealt exclusively with various pain syndromes, this new volume covers the entire spectrum of PNS applications. Written by recognized authorities in their respective fields, the chapters of this title describe the use of PNS in the management of neurological, psychiatric, otorhinolaryngological, cardiovascular, pulmonary, colorectal and genitourinary disorders. To reflect the complexity of the regulatory process, the book ends with a special chapter dedicated to the current state of approval of different PNS devices. This book will be of great value to all those who deal with neuromodulation, including clinicians who select PNS candidates, surgeons and other specialists who implant PNS devices, and researchers and engineers who work on making the stimulators safer and more effective.

Peripheral Nerve StimulationPeripheral Nerve Stimulation



All chapters contain original information making this book an invaluable reference for all who deal with the management of severe and chronic pain - including neurosurgeons and neurosurgical trainees, pain specialists and practitioners, ...

Author: Konstantin V. Slavin

Publisher: Karger Medical and Scientific Publishers

ISBN: 9783805594882

Category:

Page: 223

View: 228

In a rapidly growing field of neuromodulation against pain, this excellent publication presents a unique compilation of the latest theoretical and practical information for electrical stimulation of the peripheral nerves. Chapters cover the use of peripheral nerve stimulation in particular indications such as migraine, cluster headache, pain in Chiari malformation and fibromyalgia, as well as in specific body parts such as head and neck, trunk, and extremities. Furthermore, chapters on history, technical aspects, mechanism of action, terminology, complications and other important aspects of this pain-relieving modality give you a full overview of the field. Written by leading experts, this publication provides a comprehensive and updated summary of the currently available scientific information on peripheral nerve stimulation. All chapters contain original information making this book an invaluable reference for all who deal with the management of severe and chronic pain - including neurosurgeons and neurosurgical trainees, pain specialists and practitioners, anesthesiologists and neurologists.

Nitric Oxide and the Peripheral Nervous SystemNitric Oxide and the Peripheral Nervous System



This volume provides an overview of nitric oxide (NO) in the peripheral nervous system.

Author: Noboru Toda

Publisher:

ISBN: CORNELL:31924089566941

Category:

Page: 183

View: 852

This volume provides an overview of nitric oxide (NO) in the peripheral nervous system. It covers aspects ranging from the molecular biology and distribution of neuronal nitric oxide synthase, through the physiological and pathophysiological roles of NO in various nitrergic systems.

Strategies for Optogenetic Stimulation of Deep Tissue Peripheral NervesStrategies for Optogenetic Stimulation of Deep Tissue Peripheral Nerves



The work is important because it lays the foundation for future advancements in optogenetic peripheral nerve stimulation in both a scientific and clinical context.

Author: Benjamin E. Maimon

Publisher:

ISBN: OCLC:1051216145

Category:

Page: 190

View: 184

Optogenetic technologies have been the subject of great excitement within the scientific community for their ability to demystify complex neurophysiological pathways in the central and peripheral nervous systems. Optogenetics refers to the transduction of mammalian cells with a light-sensitive transmembrane protein, called an opsin, such that illumination of the target tissue initiates depolarization; in the case of a neuron, illumination results in the firing of an action potential that can control downstream physiology. The excitement surrounding optogenetics has also extended to the clinic with a human trial using the opsin ChR2 in the treatment of retinitis pigmentosa currently underway and several more trials potentially planned for the near future. In this thesis, we focus on the use of viral techniques to transduce peripheral nerve tissue to be responsive to light. We characterize the properties of optogenetic peripheral nerve transduction, optimizing for variables such as expression strength, wavelength specificity, and time-course of expression. Within the scope of this thesis, three new methods for optogenetic peripheral nerve stimulation are described: (1) a method for optogenetic motor nerve control using transdermal illumination, (2) a method employing unique wavelengths to selectively target optogenetic subsets of motor nerves, and (3) a method for extending optogenetic expression strength and timecourse. The work is important because it lays the foundation for future advancements in optogenetic peripheral nerve stimulation in both a scientific and clinical context.

Microelectronic Implants for Central and Peripheral Nervous System Overview of Circuit and System TechnologyMicroelectronic Implants for Central and Peripheral Nervous System Overview of Circuit and System Technology



Professor Ker is on the Board of Amazingneuron. The Other Topic Editors Declare no Competing Interests With Regards to the Research Topic Theme.

Author: Morris (Ming-Dou) Ker

Publisher: Frontiers Media SA

ISBN: 9782889740239

Category:

Page:

View: 711

Professor Ker is on the Board of Amazingneuron. The Other Topic Editors Declare no Competing Interests With Regards to the Research Topic Theme.