Dipak K. Das, Ole Vang. G The New York Academy of Sciences 1 Published by Blackwell Publishing On behalf of the New York Academy of Sciences Boston , Massachusetts 2011 ANNALS OF THE NEW YORK of VOLUME 1215 ACADEMY OF.
Author: Dipak K. Das
This volume presents manuscripts stemming from the conference entitled "Resveratrol 2010: First International Conference of Resveratrol and Health," held September 13-16, 2010 in Copenhagen, Denmark"--Table of contents page.
Resveratrol and neurodegenerative diseases: Activation of SIRT1 as the potential pathway towards neuroprotection. ... Resveratrol in cardiovascular health and disease. Annals of the NY academy of sciences, Vol. 1215, pp.
Author: Raymond Chuen-Chung Chang
Publisher: BoD – Books on Demand
Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, pathological mechanisms, drug screening methodology and new therapeutic interventions. Other chapters discuss how hormones and health food supplements affect disease progression of neurodegenerative diseases. From a more technical point of view, some chapters deal with the aggregation of prion proteins in prion diseases. An additional chapter to discuss application of stem cells. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.
Walle T (2011) Bioavailability of resveratrol. Ann NY Acad Sci. Vol. 1215, No. (Jan 2011):pp. (9-15), 1749-6632 (Electronic) Wang F, Nguyen M, Qin FX & Tong Q (2007) SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric ...
Author: David Finkelstein
Publisher: BoD – Books on Demand
Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in the substantia nigra have already been destroyed. This degeneration progresses despite the current therapies until the cell loss is so great that the quality of normal life is compromised. The dopamine precursor levodopa is the most valuable drug currently available for the treatment of PD. However for most PD patients, the optimal clinical benefit from levodopa decreases around five to six years of treatment. The aim of the chapters of this book is to work towards an understanding in the mechanisms of degeneration and to develop disease modifying therapies.
Evid Based Complement Alternat Med 2013:851267 Mukhopadhyay P, Pacher P, Das DK (2011) MicroRNA signatures of resveratrol in the ischemic heart. Ann NY Acad Sci 1215:109–116 Nakou ES, Mavrakis H, Vardas PE (2012) Are ...
Author: Munir Ozturk
Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq. The importance of plants as medicine is further supported by archeological evidence from Asia and the Middle East. Today, around 1.4 billion people in South Asia alone have no access to modern health care, and rely instead on traditional medicine to alleviate various symptoms. On a global basis, approximately 50 to 80 thousand plant species are used either natively or as pharmaceutical derivatives for life-threatening conditions that include diabetes, hypertension and cancers. As the demand for plant-based medicine rises, there is an unmet need to investigate the quality, safety and efficacy of these herbals by the “scientific methods”. Current research on drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, analytical, and molecular techniques. For instance, high throughput robotic screens have been developed by industry; it is now possible to carry out 50,000 tests per day in the search for compounds which act on a key enzyme or a subset of receptors. This and other bioassays thus offer hope that one may eventually identify compounds for treating a variety of diseases or conditions. However, drug development from natural products is not without its problems. Frequent challenges encountered include the procurement of raw materials, the selection and implementation of appropriate high-throughput bioassays, and the scaling-up of preparative procedures. Research scientists should therefore arm themselves with the right tools and knowledge in order to harness the vast potentials of plant-based therapeutics. The main objective of Plant and Human Health is to serve as a comprehensive guide for this endeavor. Volume 1 highlights how humans from specific areas or cultures use indigenous plants. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the third world and have slowly taken roots as alternative medicine in the West. The integration of modern science with traditional uses of herbal drugs is important for our understanding of this ethnobotanical relationship. Volume 2 deals with the phytochemical and molecular characterization of herbal medicine. Specifically, it will focus on the secondary metabolic compounds which afford protection against diseases. Lastly, Volume 3 focuses on the physiological mechanisms by which the active ingredients of medicinal plants serve to improve human health. Together this three-volume collection intends to bridge the gap for herbalists, traditional and modern medical practitioners, and students and researchers in botany and horticulture.
N Engl J Med 336:1131–1141 Petrovski G, Gurusamy N, Das DK (2011) Resveratrol in cardiovascular health and disease. Ann N Y Acad Sci 1215:22–33 Sahin E, Colla S, Liesa M, Moslehi J, Muller FL, Guo M, Cooper M, Kotton D, Fabian AJ, ...
Author: M.A. Hayat
This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.
... Hibiscus sabdariffa Linnaeus (Malvaceae), curcumin and resveratrol as alternative medicinal agents against metabolic syndrome. Cardiovasc. Hematol. Agents Med. Chem. 2013, 11, 25–37. [CrossRef][PubMed] Alarcon-Aguilar, F.J.; ...
Author: Maurizio Battino
This book is a printed edition of the Special Issue "Antioxidants in Health and Disease" that was published in Nutrients
Volume 3 Giuseppe Grosso ... 2011, 1215, 72–78. ... [CrossRef] [PubMed] Yáñez, M.; Fraiz, N.; Cano, E.; Orallo, F. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase ...
Author: Giuseppe Grosso
This book is a printed edition of the Special Issue " Effects of Polyphenol-Rich Foods on Human Health" that was published in Nutrients
J Nutr 130:2243–2250 Baile CA, Yang J-Y, Rayalam S et al (2011) Effect of resveratrol on fat mobilization. Ann New York Acad Sci 1215:40–47. doi:10.1111/j.1749-6632.2010.05845.x Barone E, Calabrese V, ...
Author: Geoffrey R. Dixon
This Trilogy explains “What is Horticulture?”. Volume three of Horticulture: Plants for People and Places presents readers with detailed accounts of the scientific and scholastic concepts which interact with the arts and humanities and which now underpins the rapidly evolving subject of Social Horticulture. This discipline transcends the barriers between science, medicine and the arts. This volume covers:- Horticulture and Society, Diet and Health, Psychological Health, Wildlife, Horticulture and Public Welfare, Education, Extension, Economics, Exports and Biosecurity, Scholarship and Art, Scholarship and Literature, Scholarship and History and the relationship between Horticulture and Gardening. This volume brings the evolution of the Discipline and Vocation of Horticulture firmly into the 21st Century. It covers new ground by providing a detailed analysis of the value of Horticulture as a force for enhancing society in the forms of social welfare, health and well-being, how knowledge is transferred within and between generations, and the place of Horticulture in the Arts and Humanities. Substantial emphasis is given to the relationships between health, well-being and plants by the internationally acclaimed authors who have contributed accounts of their work in this book.