Physiology Biophysics and Biomedical EngineeringPhysiology Biophysics and Biomedical Engineering



Physiology, Biophysics and Biomedical Engineering provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena.

Author: Andrew W Wood

Publisher: Taylor & Francis

ISBN: 9781466552791

Category:

Page: 782

View: 925

Physiology, Biophysics and Biomedical Engineering provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It covers the physical phenomena of electricity, pressure, and flow along with the adaptation of the physics of the phenomena to the special conditions and constraints of biological systems. While the text focuses on human biological systems, some of the principles also apply to plants, bacteria, and other animals. The first section of the book presents a general introduction to physiological systems and describes specialized methods used to record electrical events from biological tissue. The next part examines molecules involved in cell transport and signaling as well as the proteins relevant in cells’ ability to contract and generate tension. The text goes on to cover the properties of the heart, blood, and circulation and the monitoring of cardiac and circulatory function. It then discusses the importance of the interrelationship of pressures and flows in organ systems, such as the lungs and kidneys, and details the organization and function of the nervous system. After focusing on the systems used to monitor signals, the book explores modeling, biomechanics, and emerging technologies, including the progressive miniaturization of sensors and actuators in biomedical engineering. Developed from the authors’ courses in medical biophysics and biomedical instrumentation, this book shows how biophysics and biomedical engineering have advanced modern medicine. It brings together the physical principles underlying human physiological processes and the physical methods used to monitor these processes. Requiring only basic mathematical knowledge, the text supplements mathematical formulae with qualitative explanations and illustrations to encourage an intuitive grasp on the processes discussed.

Intermediate Physics for Medicine and BiologyIntermediate Physics for Medicine and Biology



This classic text has been used in over 20 countries by advanced undergraduate and beginning graduate students in biophysics, physiology, medical physics, neuroscience, and biomedical engineering.

Author: Russell K. Hobbie

Publisher: Springer

ISBN: 9783319126821

Category:

Page: 629

View: 535

This classic text has been used in over 20 countries by advanced undergraduate and beginning graduate students in biophysics, physiology, medical physics, neuroscience, and biomedical engineering. It bridges the gap between an introductory physics course and the application of physics to the life and biomedical sciences. Extensively revised and updated, the fifth edition incorporates new developments at the interface between physics and biomedicine. New coverage includes cyclotrons, photodynamic therapy, color vision, x-ray crystallography, the electron microscope, cochlear implants, deep brain stimulation, nanomedicine, and other topics highlighted in the National Research Council report BIO2010. As with the previous edition, the first half of the text is primarily biological physics, emphasizing the use of ideas from physics to understand biology and physiology, and the second half is primarily medical physics, describing the use of physics in medicine for diagnosis (mainly imaging) and therapy. Prior courses in physics and in calculus are assumed. Intermediate Physics for Medicine and Biology is also ideal for self study and as a reference for workers in medical and biological research. Over 850 problems test and enhance the student's understanding and provide additional biological examples. A solutions manual is available to instructors. Each chapter has an extensive list of references.

Quantifying Morphology and Physiology of the Human Body Using MRIQuantifying Morphology and Physiology of the Human Body Using MRI



... Xiaoyi Jiang, and Klaus Schafers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew Wood (Ed) Proton Therapy Physics Harald Paganetti (Ed) ...

Author: L. Tugan Muftuler

Publisher: CRC Press

ISBN: 9781439852651

Category:

Page: 525

View: 871

In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introduce new frontiers of study into disease mechanisms.

The Physiological Measurement HandbookThe Physiological Measurement Handbook



Biomedical. Engineering ... and Klaus Schäfers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew Wood (Ed) Proton Therapy Physics Harald ...

Author: John G. Webster

Publisher: CRC Press

ISBN: 9781439808481

Category:

Page: 616

View: 993

The Physiological Measurement Handbook presents an extensive range of topics that encompass the subject of measurement in all departments of medicine. The handbook describes the use of instruments and techniques for practical measurements required in medicine. It covers sensors, techniques, hardware, and software as well as information on processing systems, automatic data acquisition, reduction and analysis, and their incorporation for diagnosis. Suitable for both instrumentation designers and users, the handbook enables biomedical engineers, scientists, researchers, students, health care personnel, and those in the medical device industry to explore the different methods available for measuring a particular physiological variable. It helps readers select the most suitable method by comparing alternative methods and their advantages and disadvantages. In addition, the book provides equations for readers focused on discovering applications and solving diagnostic problems arising in medical fields not necessarily in their specialty. It also includes specialized information needed by readers who want to learn advanced applications of the subject, evaluative opinions, and possible areas for future study.

Fundamentals of Human PhysiologyFundamentals of Human Physiology



The book addresses a broad range of topics, including: the statics and dynamics of circulation; muscle and sarcomere force-length and force-velocity relations, together with their mechanisms and functional consequences; subdivisions and ...

Author: Giovanni Cavagna

Publisher: Springer

ISBN: 9783030194048

Category:

Page: 249

View: 113

This textbook explores the fundamental qualitative and quantitative aspects of human physiology. It approaches biological and physiological processes and phenomena from a quantitative perspective, revealing how physiological problems can be mathematically formulated starting from simple laws of physics. The book addresses a broad range of topics, including: the statics and dynamics of circulation; muscle and sarcomere force-length and force-velocity relations, together with their mechanisms and functional consequences; subdivisions and meaning of the heat produced by muscle; locomotion, statics and dynamics of respiration; diffusion of gases and acid base equilibrium; phonation; general functions of the kidney and of the different sections of the nephron; changes in clearance with a substance’s plasmatic concentration; pH regulation and the kidney; Donnan’s equilibrium and its consequences; and the Nernst equation. The book offers the ideal learning resource for students of human physiology courses in medicine and biomedicine, as well as biomedical engineering and biophysics graduate students. An elementary grasp of mathematics and physics is sufficient to understand the content.

Biomedical Signals and Sensors IIIBiomedical Signals and Sensors III



As the third volume in the author’s series on “Biomedical Signals and Sensors,” this book explains in a highly instructive way how electric, magnetic and electromagnetic fields propagate and interact with biological tissues.

Author: Eugenijus Kaniusas

Publisher: Springer

ISBN: 9783319749174

Category:

Page: 609

View: 103

As the third volume in the author’s series on “Biomedical Signals and Sensors,” this book explains in a highly instructive way how electric, magnetic and electromagnetic fields propagate and interact with biological tissues. The series provides a bridge between physiological mechanisms and theranostic human engineering. The first volume focuses on the interface between physiological mechanisms and the resultant biosignals that are commonplace in clinical practice. The physiologic mechanisms determining biosignals are described from the cellular level up to the mutual coordination at the organ level. In turn, the second volume considers the genesis of acoustic and optic biosignals and the associated sensing technology from a strategic point of view. This third volume addresses the interface between electric biosignals and biomedical sensors. Electric biosignals are considered, starting with the biosignal formation path to biosignal propagation in the body and finally to the biosignal sensing path and the recording of the signal. The series also emphasizes the common features of acoustic, optic and electric biosignals, which are ostensibly entirely different in terms of their physical nature. Readers will learn how these electric, magnetic and electromagnetic fields propagate and interact with biological tissues, are influenced by inhomogeneity effects, cause neuromuscular stimulation and thermal effects, and finally pass the electrode/tissue boundary to be recorded. As such, the book helps them manage the challenges posed by the highly interdisciplinary nature of biosignals and biomedical sensors by presenting the basics of electrical engineering, physics, biology and physiology that are needed to understand the relevant phenomena.

Quantitative Human PhysiologyQuantitative Human Physiology



This book explores how component behavior produces system behavior in physiological systems.

Author: Joseph J Feher

Publisher: Academic Press

ISBN: 9780128011546

Category:

Page: 1008

View: 790

Quantitative Human Physiology: An Introduction is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. Features a quantitative approach that includes physical and chemical principles Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION Expansion of many sections to include relevant information Addition of many new figures and re-drawing of other figures to update our understanding and clarify difficult areas Substantial updating of the text to reflect newer research results Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit Addition of new problems within the problem sets Addition of commentary to power point presentations

Computer Simulation and Data Analysis in Molecular Biology and BiophysicsComputer Simulation and Data Analysis in Molecular Biology and Biophysics



The fields of biological and medical physics and biomedical engineering are ... Japan Olaf S. Andersen, Department of Physiology, Biophysics & Molecular ...

Author: Victor Bloomfield

Publisher: Springer Science & Business Media

ISBN: 9781441900838

Category:

Page: 321

View: 718

This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive.

Signals and Systems in Biomedical Engineering Physiological Systems Modeling and Signal ProcessingSignals and Systems in Biomedical Engineering Physiological Systems Modeling and Signal Processing



This book shows that systems modeling can be used to develop simulations of physiological systems, which use formal relations between the underlying processes and the observed measurements.

Author: Suresh R. Devasahayam

Publisher: Springer

ISBN: 9789811335310

Category:

Page: 468

View: 143

Physiology is a set of processes that maintain homeostasis, and physiological measurement is a means of observing these processes. Systems theory and signal processing offer formal tools for the study of processes and measured quantities. This book shows that systems modeling can be used to develop simulations of physiological systems, which use formal relations between the underlying processes and the observed measurements. The inverse of such relations suggest signal processing tools that can be applied to interpret experimental data. Both signal processing and systems modeling are invaluable in the study of human physiology. Discussing signal processing techniques ranging from filtering and spectrum analysis to wavelet analysis, the book uses graphs and analogies to supplement the mathematics and make the book more accessible to physiologists and more interesting to engineers. Physiological systems modeling helps in both gaining insight and generating methods of analysis. This book shows how numerical computation with graphical display, haptics and multimedia can be used to simulate physiological systems. In this third edition the simulations are more closely related to clinical examination and experimental physiology than in previous editions. Detailed models of nerve and muscle at the cellular and systemic levels, and simplified models of cardiovascular blood flow provide examples for the mathematical methods and computer simulations. Several of the models are sufficiently sophisticated to be of value in understanding real world issues like neuromuscular disease. The book features expanded problem sets and a link to extra downloadable material containing simulation programs that are solutions to the theory developed in the text.

Statistical Computing in Nuclear ImagingStatistical Computing in Nuclear Imaging



Biomedical. Engineering ... and Klaus Schäfers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew Wood (Ed) Proton Therapy Physics Harald ...

Author: Arkadiusz Sitek

Publisher: CRC Press

ISBN: 9781498729307

Category:

Page: 275

View: 894

Statistical Computing in Nuclear Imaging introduces aspects of Bayesian computing in nuclear imaging. The book provides an introduction to Bayesian statistics and concepts and is highly focused on the computational aspects of Bayesian data analysis of photon-limited data acquired in tomographic measurements. Basic statistical concepts, elements of decision theory, and counting statistics, including models of photon-limited data and Poisson approximations, are discussed in the first chapters. Monte Carlo methods and Markov chains in posterior analysis are discussed next along with an introduction to nuclear imaging and applications such as PET and SPECT. The final chapter includes illustrative examples of statistical computing, based on Poisson-multinomial statistics. Examples include calculation of Bayes factors and risks as well as Bayesian decision making and hypothesis testing. Appendices cover probability distributions, elements of set theory, multinomial distribution of single-voxel imaging, and derivations of sampling distribution ratios. C++ code used in the final chapter is also provided. The text can be used as a textbook that provides an introduction to Bayesian statistics and advanced computing in medical imaging for physicists, mathematicians, engineers, and computer scientists. It is also a valuable resource for a wide spectrum of practitioners of nuclear imaging data analysis, including seasoned scientists and researchers who have not been exposed to Bayesian paradigms.

Radiosensitizers and Radiochemotherapy in the Treatment of CancerRadiosensitizers and Radiochemotherapy in the Treatment of Cancer



... and Kwan-Hoong Ng Other recent books in the series: The Physiological ... Klaus Schäfers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew ...

Author: Shirley Lehnert

Publisher: CRC Press

ISBN: 9781439829028

Category:

Page: 548

View: 227

Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals. At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy. In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.

Introduction to Biomedical EngineeringIntroduction to Biomedical Engineering



The modeling techniques developed in this chapter are intimately tied to many other interdisciplinary areas, such as physiology, biophysics, ...

Author: John Enderle, Ph.D.

Publisher: Academic Press

ISBN: 9780122386626

Category:

Page: 1118

View: 892

Since publication in 1999, the first edition of Introduction to Biomedical Engineering has dominated the market of biomedical engineering texts. Under the direction of John Enderle, Susan Blanchard and Joe Bronzino, leaders in the field have contributed chapters on the most relevant subjects for biomedical engineering students. These chapters coincide with courses offered in all biomedical engineering programs so that it can be used at different levels for a variety of courses of this evolving field. Both Enderle and Blanchard are on the Accreditation Board for Engineering and Technology (ABET), the body that sets the standard for US-based engineering programs. These standards have been used as a guideline for examples and pedagogy. New to this edition: Computational Biology, Medical Imaging, Genomics and Bioinformatics. · 60% update from first edition to reflect the developing field of biomedical engineering. · Pioneer title in the Academic Press Series in Biomedical Engineering · Over 4,000 units of first edition sold · MatLab examples included in every chapter

Diagnostic EndoscopyDiagnostic Endoscopy



Series in Medical Physics and Biomedical Engineering Series Editors: John G ... Schäfers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew ...

Author: Haishan Zeng

Publisher: Taylor & Francis

ISBN: 9781420083460

Category:

Page: 272

View: 963

Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors’ graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case studies to familiarize readers with the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various microscopic endoscopy imaging modalities. It covers basic optics, details of design and biomedical uses, as well as microscopic endoscopy, and endoscopic spectroscopy.

Radiation Protection in Medical Imaging and Radiation OncologyRadiation Protection in Medical Imaging and Radiation Oncology



... in Nuclear Imaging Arkadiusz Sitek The Physiological Measurement Handbook ... Schäfers (Eds) Physiology, Biophysics, and Biomedical Engineering Andrew ...

Author: Richard J. Vetter

Publisher: CRC Press

ISBN: 9781482245387

Category:

Page: 512

View: 322

Radiation Protection in Medical Imaging and Radiation Oncology focuses on the professional, operational, and regulatory aspects of radiation protection. Advances in radiation medicine have resulted in new modalities and procedures, some of which have significant potential to cause serious harm. Examples include radiologic procedures that require ve

Principles and Models of Biological TransportPrinciples and Models of Biological Transport



This text is designed for a first course in biological mass transport, and the material in it is presented at a level that is appropriate to advanced undergraduates or early graduate level students.

Author: Morton H. Friedman

Publisher: Springer Science & Business Media

ISBN: 9783662024676

Category:

Page: 260

View: 428

This text is designed for a first course in biological mass transport, and the material in it is presented at a level that is appropriate to advanced undergraduates or early graduate level students. Its orientation is somewhat more physical and mathematical than a biology or standard physiology text, reflecting its origins in a transport course that I teach to undergraduate (and occasional graduate) biomedical engineering students in the Whiting School of Engineering at Johns Hopkins. The audience for my cours- and presumably for this text - also includes chemical engineering undergraduates concentrating in biotechnology, and graduate students in biophysics. The organization of this book differs from most texts that at tempt to present an engineering approach to biological transport. What distinguishes biological transport from other mass transfer processes is the fact that biological transport is biological. Thus, we do not start with the engineering principles of mass transport (which are well presented elsewhere) and then seek biological ap plications of these principles; rather, we begin with the biological processes themselves, and then develop the tools that are needed to describe them. As a result, more physiology is presented in this text than is often found in books dealing with engineering applica tions in the life sciences.