Alzheimer s and Parkinson s DiseasesAlzheimer s and Parkinson s Diseases

Since levodopa 1s hardly used for Indications other than Parkinson disease, and since advanced cases of non-treated Parkinsonism are not available (or cannot be tested), this theory was hard to disprove.

Author: Abraham Fisher

Publisher: Springer

ISBN: UOM:39015010149808


Page: 736

View: 104

This book is the outcome of an international conference, held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. This was the 30th in a series of the annual OHOLO Conferences, sponsored by the Israel Institute for Biological Research. Participants in this Conference consisted of scientists from four teen countries; represented a broad spectrum of research interests; and included a well-balanced representation from academia, clinical institutions and pharmaceutical industry. The book includes talks, poster sessions, and a comprehensive general discussion, all from the proceedings of this conference. In the interest of assuring a rapid publication of the novel infor mation reviewed, this book has been prepared in camera-ready format. We are cognizant of the fact that several typographical errors may exist in the text, and that there are variations in style and typeface of the var ious chapters. This, we felt, was a reasonable compromise for the sake of speed and efficient transmission of valuable scientific information. No body is perfect . •••• The success of the conference, and hence the quality of this book are attributable to the extensive efforts of a large number of extremely capable individuals. These include members of the Scientific Organizing Committee, and the Technical staff of the OHOLO Organization. Of course, the conference could not have succeeded without the high quality of the presentations, and the enthusiastic participation of the contributing scientists.

Parkinson s Disease and Movement DisordersParkinson s Disease and Movement Disorders

296 Parkinson's Disease and Movement Disorders 129. Kosel S , Grasbon - Frodl EM , Hagenah JM , Graeber MB , Vieregge P. Parkinson disease : analysis of mitochondrial DNA in monozygotic twins . Neurogenetics 2000 ; 2 : 227-230 . 130.

Author: Joseph Jankovic

Publisher: Lippincott Williams & Wilkins

ISBN: 0781778816


Page: 748

View: 718

Written by an international group of renowned experts, the Fifth Edition of this premier reference provides comprehensive, current information on the genetics, pathophysiology, diagnosis, medical and surgical treatment, and behavioral and psychologic concomitants of all common and uncommon movement disorders. Coverage includes Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. This edition features extensive updates on genetics, imaging, and therapeutics of Parkinson's disease, other parkinsonian disorders, and all hyperkinetic movement disorders. A bound-in CD-ROM, Video Atlas of Movement Disorders, demonstrates the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.

Parkinson s Disease Second EditionParkinson s Disease Second Edition

Hampe, C. et al., Biochemical analysis of Parkinson's diseasecausing variants of parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Hum Mol Genet, 2006. 15(13): 2059–2075. Hedrich, K. et al., DJ-1 (PARK7) mutations ...

Author: Ronald F. Pfeiffer

Publisher: CRC Press

ISBN: 9781439807149


Page: 1335

View: 699

In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD.

Current Concepts in Parkinson s Disease ResearchCurrent Concepts in Parkinson s Disease Research

... and immediate knowledge to clinicians, including neurologists, internists, and psychiatrists, who want to obtain a rapid but thorough understanding of the frontiers of research and clinical treatment regarding Parkinson Disease.

Author: Jay S. Schneider

Publisher: Seattle : Toronto : Hogrefe & Huber

ISBN: UOM:39015029459545


Page: 480

View: 919

This book offers knowledge to clinicians, such as neurologists, internists, and psychiatrists, who wish to obtain an understanding of the frontiers of both the research and clinical treatment regarding Parkinson's disease.

Balance Dysfunction in Parkinson s DiseaseBalance Dysfunction in Parkinson s Disease

Objective gait and balance impairments relate to balance confidence and perceived mobility in people with Parkinson disease. Physical Therapy 2016;96(11):1734e43. 98. Curtze C, Nutt JG, Carlson-Kuhta P, Mancini M, Horak FB.

Author: Martina Mancini

Publisher: Academic Press

ISBN: 9780128138755


Page: 226

View: 683

Balance Dysfunction in Parkinson’s Disease: Basic Mechanisms to Clinical Management presents the most updated information on a variety of topics. Sections help clinicians evaluate the types of balance control issues, dynamic balance dysfunction during turning, and the effects of medication, deep brain stimulation, and rehabilitation intervention on balance control. This book is the first to review the four main postural control systems and how they are affected, including balance during quiet stance, reactive postural adjustments to external perturbations, anticipatory postural adjustments in preparation for voluntary movements, and dynamic balance control during walking and turning. In addition, the book's authors summarize the effects of levodopa, deep brain stimulation, and rehabilitation intervention for each balance domain. This book is recommended for anyone interested in how and why balance control is affected by PD. Provides the first comprehensive review of research to date on balance dysfunctions in Parkinson's disease Discusses how to translate current neuroscience research into practice regarding neural control of balance Provides evidence on the effects of current interventions on balance control

Rating Scales in Parkinson s DiseaseRating Scales in Parkinson s Disease

Fatigue in Parkinson's disease: a review. Mov Disord. 2007;22:297–308. 2. Hagell P, Brundin L. Towards an understanding of fatigue in Parkinson disease. J Neurol Neurosurg Psychiatry. 2009;80:489–492. 3. Schifitto G, Friedman JH, ...

Author: Cristina Sampaio

Publisher: Oxford University Press

ISBN: 9780199783106


Page: 342

View: 353

For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another.

Cognitive Impairment and Dementia in Parkinson s DiseaseCognitive Impairment and Dementia in Parkinson s Disease

33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 Kumru H, Santamaria J, Tolosa E, Iranzo A. Relation between subtype of Parkinson's disease and REM sleep behavior disorder. Sleep Med 2007; 8: 779–83.

Author: Murat Emre

Publisher: Oxford University Press, USA

ISBN: 9780199564118


Page: 288

View: 935

In this edited volume, experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson's disease, including epidemiology, spectrum of clinical features, pathology, neurochemistry and genetics, findings in auxillary investigations, and the relation to other neurodegenerative disorders.

Managing Parkinson s Disease With a Multidisciplinary PerspectiveManaging Parkinson s Disease With a Multidisciplinary Perspective

Complementary physical therapies for movement disorders in Parkinson's disease: a systematic review. Eur J Phys Rehabil Med. (2015) 51:693–704. 37. Zhong D, Xiao Q, Xiao X, Li Y, Ye J, Xia L, Jin R. Tai Chi for improving balance and ...

Author: Daniel Martinez-Ramirez

Publisher: Frontiers Media SA

ISBN: 9782889740765


Page: 121

View: 516

The Neuroscience of Parkinson s DiseaseThe Neuroscience of Parkinson s Disease

Elevated 5-S-cysteinyldopamine/homovanillic acid ratio and reduced homovanillic acid in cerebrospinal fluid: Possible markers for and potential insights into the pathophysiology of Parkinson's disease. Journal of Neural Transmission, ...

Author: Colin R. Martin

Publisher: Academic Press

ISBN: 9780128159590


Page: 1612

View: 925

The Neuroscience of Parkinson’s Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease