The Emperor s New DrugsThe Emperor s New Drugs



This is not a book about alternative medicine and its outlandish claims. This is a book about fantasy and wishful thinking in the heart of clinical medicine, about the seductions of myth, and the final stubbornness of facts.

Author: Irving Kirsch

Publisher: Random House

ISBN: 9781409086352

Category:

Page: 240

View: 481

Everyone knows that antidepressant drugs are miracles of modern medicine. Professor Irving Kirsch knew this as well as anyone. But, as he discovered during his research, there is a problem with what everyone knows about antidepressant drugs. It isn't true. How did antidepressant drugs gain their reputation as a magic bullet for depression? And why has it taken so long for the story to become public? Answering these questions takes us to the point where the lines between clinical research and marketing disappear altogether. Using the Freedom of Information Act, Kirsch accessed clinical trials that were withheld, by drug companies, from the public and from the doctors who prescribe antidepressants. What he found, and what he documents here, promises to bring revolutionary change to the way our society perceives, and consumes, antidepressants. The Emperor's New Drugs exposes what we have failed to see before: depression is not caused by a chemical imbalance in the brain; antidepressants are significantly more dangerous than other forms of treatment and are only marginally more effective than placebos; and, there are other ways to combat depression, treatments that don't only include the empty promise of the antidepressant prescription. This is not a book about alternative medicine and its outlandish claims. This is a book about fantasy and wishful thinking in the heart of clinical medicine, about the seductions of myth, and the final stubbornness of facts.

The Antidepressant Fact BookThe Antidepressant Fact Book



Hard-hitting and enlightening, every current, former, and prospective antidepressant-user will want to read this book.

Author: Peter Breggin

Publisher: Da Capo Lifelong Books

ISBN: 073820451X

Category:

Page: 240

View: 99

Known as "the Ralph Nader of psychiatry," Dr. Peter Breggin has been the medical expert in countless court cases involving the use or misuse of psychoactive medications. This unusual position has given him unprecedented access to private pharmaceutical research and correspondence files, information from which informs this straight-talking guide to the most prescribed and controversial category of American drugs: antidepressants. From how these drugs work in the brain to how they treat (or don't treat) depression and obsessive-compulsive, panic, and other disorders; from the documented side and withdrawal effects to what every parent needs to know about antidepressants and teenagers, The Anti-Depressant Fact Book is up-to-the minute and easy-to-access. Hard-hitting and enlightening, every current, former, and prospective antidepressant-user will want to read this book.

The Antidepressant SolutionThe Antidepressant Solution



It is the first book to call attention to the drugs' catch-22: Although many people are ready to go off these drugs, they continue to take them because either the patient or the doctor mistakes antidepressant withdrawal for depressive ...

Author: Joseph Glenmullen

Publisher: Simon and Schuster

ISBN: 9780743288989

Category:

Page: 272

View: 952

With the FDA's warning that antidepressants may cause agitation, anxiety, hostility, and even violent or suicidal tendencies, these medications are at the forefront of national legal news. Harvard physician Joseph Glenmullen has led the charge to warn the public that antidepressants are overprescribed, underregulated, and, especially, misunderstood in their side and withdrawal effects. Now he offers a solution! More than twenty million Americans -- including over one million teens and children -- take one of today's popular antidepressants, such as Paxil, Zoloft, or Effexor. Dr. Glenmullen recognizes the many benefits of antidepressants and prescribes them to his patients, but he is also committed to warning the public of the dangers associated with overprescription. Dr. Glenmullen's last book, Prozac Backlash, sounded the alarm about possible dangers. The Antidepressant Solution provides the remedy. It is the first book to call attention to the drugs' catch-22: Although many people are ready to go off these drugs, they continue to take them because either the patient or the doctor mistakes antidepressant withdrawal for depressive relapse. The Antidepressant Solution offers an easy, step-by-step guide for patients and their doctors. Written by the premier authority in the field, The Antidepressant Solution is an invaluable book for all those concerned with going through the process -- from friends and family members to doctors and patients themselves.

The Antidepressant EraThe Antidepressant Era



In this work Healy chronicles the history of psychopharmacology, from the discovery of chlorpromazine in 1951, to current battles over whether powerful chemical compounds should replace psychotherapy.

Author: David Healy

Publisher: Harvard University Press

ISBN: 0674039580

Category:

Page: 317

View: 604

In this work Healy chronicles the history of psychopharmacology, from the discovery of chlorpromazine in 1951, to current battles over whether powerful chemical compounds should replace psychotherapy. The marketing of antidepressants is included.

Antidepressant Treatment of Depression in Real world SettingsAntidepressant Treatment of Depression in Real world Settings



Geddes , J . R . , Freemantle , N . , Mason , J . , et al ( 1999 ) SSRIs versus
alternative antidepressants in depressive disorder . Cochrane Library , issue 4 .
Oxford : Update Software . - i - & Snider , R . M . ( 1987 ) Antidepressant
withdrawal ...

Author: Julien Mendlewicz

Publisher:

ISBN: UCSC:32106016261189

Category:

Page: 22

View: 988

The Evidence based Guide to Antidepressant MedicationsThe Evidence based Guide to Antidepressant Medications



This text is a must-have reference for psychiatrists and other practicing clinicians, residents-in-training, psychiatric nurses, social workers, and researchers.

Author: Anthony J. Rothschild

Publisher: American Psychiatric Pub

ISBN: 9781585624058

Category:

Page: 404

View: 645

"The Evidence-Based Guide to Antipsychotic Medications" is a table-rich, comprehensive overview of current knowledge regarding the use of antipsychotic medications to treat a broad range of psychiatric conditions, from anxiety disorders to schizophrenia.

The Antidepressant Survival ProgramThe Antidepressant Survival Program



THE ANTIDEPRESSANT PARADOX Antidepressants have offered hope and
relief to millions of people suffering from depression and have saved tens of
thousands of lives by preventing suicide . About two - thirds of people who are ...

Author: Robert J. Hedaya

Publisher: Crown

ISBN: 0609604651

Category:

Page: 292

View: 479

A psychopharmacologist and clinical psychiatrist offers his program for reducing the side effects of antidepressantsincluding weight gain, sexual dysfunction, and energy losswithout taking more drugs.

A Randomized Controlled Study Evaluating the Impact of an Antidepressant Monitoring Program on Consumer OutcomesA Randomized Controlled Study Evaluating the Impact of an Antidepressant Monitoring Program on Consumer Outcomes



Beliefs about Antidepressant Use ( BELIEF ) Bultman and Svarstad ( 2002 )
assessed three positive and five negative ... taking an antidepressant , ( 2 )
antidepressants are useful in treating depression , and ( 3 ) taking an
antidepressant is a ...

Author: Nathaniel Marc Rickles

Publisher:

ISBN: WISC:89079705489

Category:

Page: 301

View: 404

Antidepressant Effects of the Nonpeptidic Delta opioid Receptor Agonist SNC80Antidepressant Effects of the Nonpeptidic Delta opioid Receptor Agonist SNC80



In addition to antidepressant-like effects, delta-opioid receptor agonists also
produce convulsions, antinociception, and locomotor stimulation. Delta-opioid
agonist- induced convulsions have been observed in mice, rats, and monkeys (
Broom ...

Author: Emily M. Jutkiewicz

Publisher:

ISBN: UOM:39015059185689

Category:

Page:

View: 685

The Antidepressant Survival GuideThe Antidepressant Survival Guide



... and overall sense of well-being. They also cause you to pack on pounds,
especially if you're taking antidepressants. VVhat's more, they can interfere with
the beneficial effects of your antidepressants. SUGAR If you're on
antidepressants, ...

Author: Robert J. Hedaya, M.D.

Publisher: Harmony

ISBN: 9780307779625

Category:

Page: 304

View: 139

"Now patients can have the best of both worlds—freedom from depression and freedom from side effects. Dr. Robert Hedaya offers a wealth of wisdom drawn from years of clinical experience, research, and teaching. This book is a much-needed lantern in the darkness." —Norman Rosenthal, M.D., author of St. John's Wort: The Herbal Way to Feeling Good * Restore the vital vitamins, minerals, and hormones necessary to maintain good health. * Optimize your body's metabolic system. * Restore your ability to experience pleasure in life. An estimated twenty-five million Americans take antidepressants to combat depression, but most continue to cope with a host of debilitating side effects that equal, and sometimes outweigh, the medication's obvious benefits. Many doctors consider side effects such as weight gain, lethargy, and sexual dysfunction to be necessary evils. Finally, there is a doctor who refuses to trade a patient's total well-being for the treatment of depression. Clinical psychiatrist Robert J. Hedaya, M.D., has developed a comprehensive mind-body program to restore lost vitality and sex drive and control weight. A Washington Post bestseller in hardcover, his book offers a proven program of nutrition, exercise, stress reduction, and hormone supplementation that not only lessens the side effects of antidepressants but enhances their benefits as well. Now everyone can benefit from the prescription that has worked wonders for his own patients.

AntidepressantsAntidepressants



Important clinical issues as the outcome of long term treatment with antidepressants, the time of onset of the antidepressant response and the limitations of the antidepressants currently available are covered in this monograph.

Author: Brian E. Leonard

Publisher: Birkhäuser

ISBN: 9783034883443

Category:

Page: 150

View: 844

Important clinical issues as the outcome of long term treatment with antidepressants, the time of onset of the antidepressant response and the limitations of the antidepressants currently available are covered in this monograph. Leading researchers in the area of clinical and experimental psychopharmacology critically assess the progress in their specialist fields. The mechanisms of action of antidepressants are considered, followed by clinical research into the role of the hypothalamic-pituitary-adrenal axis and the immune system in the biology of depression and in response to treatment. The final chapter deals with the important chemical entities now undergoing development as antidepressants. The purpose of this monograph is not only to inform but also to stimulate research into the biology of depression and the mechanisms behind the action of effective antidepressants. This monograph is of interest to psychiatrists, psychologists, pharmacologists, neuroscientists and endocrinologists.

Antidepressants for Elderly PeopleAntidepressants for Elderly People



These are considered to be due to age-related physiological changes.

Author: K. Ghose

Publisher: Springer

ISBN: 0412324601

Category:

Page: 302

View: 748

Depression is one of the commonest problems in old age. Yet until recently, old people were systematically exduded from participating in drug trials and similar investigations. As a result, knowledge regarding incidence, natural history and management of depression in the elderly are somewhat limited. It is now well-established that old people are sensitive to most psychotropic drugs and they tend to suffer from adverse effects and side effects of antidepressant drugs more frequently than any other age group. These are considered to be due to age-related physiological changes. In addition, because of the frequent association with multiple pathology, the elderly are likely to receive polypharmacy which further complicates the management of antidepressant drug therapy. The aim of this book is to provide a comprehensive guidance on the drug therapy of depression for the dinicians involved in the health care of the elderly. In the first section, epidemiology, presentations and assessment of depression in old age and neuroendocrine abnormalities observed in patients with depression are briefly discussed. However, it mainly deals with the problems of antidepressant drug therapy, such as which antidepressant to prescribe, how to monitor efficacy and side effects, what is the adequate dose, how long to treat a single episode of depression and who requires long term medication. Information regarding pharmacology, side effects, adverse effects, drug interaction and pharmacokinetics of most currently available drugs are provided. Special emphasis has been given on continuation therapy and the choice of an antidepressant drug and their long term safety.

AntidepressantsAntidepressants



This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

Author: Matthew Macaluso

Publisher: Springer

ISBN: 9783030109493

Category:

Page: 442

View: 816

This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

AntidepressantsAntidepressants



antidepressants . Scientists do not yet know why the thyroid impacts on how well
an antidepressant works . One psychiatrist explained that , “ A depressed person
whose thyroid gland is the slightest bit underactive will respond poorly to ...

Author: Judy Monroe

Publisher: Enslow Publishers

ISBN: 0766019179

Category:

Page: 128

View: 655

Examines the social and physical effects of antidepressants.

Antidepressants and Receptor FunctionAntidepressants and Receptor Function



This book should be of interest to neuropharmacologists, psychopharmacologists, clinical pharmacologists, behavioural scientists, psychiatrists and neuroscientists.

Author: Ruth Porter

Publisher: John Wiley & Sons

ISBN: 9780470513378

Category:

Page: 304

View: 712

Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy, 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many questions remain about the mechanisms of action of such treatments and about the aetiology and pathophysiology of depression itself. Early observations centred attention on central monoamine systems, and animal studies suggested that changes in beta-adrenoceptor responsiveness were a common effect of antidepressant therapies. More recent research has encompassed many different central and peripheral receptors, time-dependent adaptational events at synapses, and the functional significance of changes in neurotransmitter systems in both humans and experimental animals. Such pharmacological studies aimed ultimately at elucidating the neurochemical basis of depression and of promoting new therapeutic approaches, provide the focus of this symposium volume. Many different methods of investigating the links between monoamine systems, depression and antidepressant treatments are described. Recent studies of receptors and of monoamine uptake sites in the brain and the periphery (e.g. in platelets and fibroblasts) are reviewed, with emphasis on alpha and beta adrenoceptors, [3H]imipramine-binding sites and serotonin receptors. The results of monitoring amine metabolites in cerebrospinal fluid and of measuring neuroendocrine, physiological and behavioural responses to pharmacological challenge are presented, providing information on monoaminergic function in depressed patients and experimental animals before, during and after treatment with antidepressant drugs or electroconvulsive shock. Genetic influences on receptor density are also discussed, as is the relevance to human depressive illness of animal models, including stress-induced behavioural depression in rats and responses to social stressors in rhesus monkeys. This book should be of interest to neuropharmacologists, psychopharmacologists, clinical pharmacologists, behavioural scientists, psychiatrists and neuroscientists.

The Search for Antidepressants An Integrative View of Drug DiscoveryThe Search for Antidepressants An Integrative View of Drug Discovery



This book is an indispensable reference for mental health care providers, students at both under-graduate and graduate levels, and neuroscientists interested in the neurobiology of MDD and recent advances towards the discovery of next ...

Author: João Quevedo

Publisher: Bentham Science Publishers

ISBN: 9781681084732

Category:

Page: 416

View: 878

Major depressive disorder (MDD) is a prevalent, chronic, and recurring mental disorder. This disorder is a leading source of disability worldwide, and is associated with excess mortality rates. Currently approved antidepressants primarily enhance, or otherwise modulate monoaminergic neurotransmission, without curing the disease. Evidence indicates that only one third of patients with MDD achieve remission after treatment with a first-line antidepressant agent. Research in the past two decades has provided valuable insights into the pathophysiological understanding of MDD. However, there is an acknowledged ‘translational gap’ in the field, and few genuinely novel antidepressants have been approved for the treatment of MDD. The Search for Anti Depressants provides readers an in-depth picture of the main pathophysiological mechanisms responsible for the development of MDD in patients. Chapters in the volume focus on possible strategies to spur the discovery of novel antidepressants. This book is an indispensable reference for mental health care providers, students at both under-graduate and graduate levels, and neuroscientists interested in the neurobiology of MDD and recent advances towards the discovery of next generation antidepressants.

The Antidepressant AntidoteThe Antidepressant Antidote



If so, this book is for you. In The Antidepressant Antidote: Five Steps to Get Off Antidepressants Safely and Effectively, Bethany Butzer, Ph.D. provides practical and proven techniques to help you get off antidepressants once and for all.

Author: Bethany Butzer, Ph.D.

Publisher: BalboaPress

ISBN: 1452500444

Category:

Page: 188

View: 137

Do you want to get off antidepressants and move toward a more full and balanced life? Have you tried several times to get off antidepressants, only to end up right back on them? If so, this book is for you. In The Antidepressant Antidote: Five Steps to Get Off Antidepressants Safely and Effectively, Bethany Butzer, Ph.D. provides practical and proven techniques to help you get off antidepressants once and for all. This life-enhancing 5-step program will teach you: • How to get the support you need as you taper off antidepressants. • Tips to deal with the withdrawal effects that can arise when reducing your antidepressant dose. • Techniques to let go of stress, anxiety, sadness, and depression. • Smart choices to move you toward the type of life you desire. • Strategies to stay off antidepressants over the long term. In this book, Dr. Butzer doesn’t stand up on an ivory tower and tell you what to do. She took antidepressants for 6 years, and after several failed attempts she finally managed to get off the medication for good. She offers moving, real-life stories from her own experiences to show you how to bring the principles in this book to life. Written by an expert in psychology who understands antidepressants both personally and professionally, The Antidepressant Antidote provides a holistic 5-step program to help you kick your antidepressant habit for good.